Case 1 History

Presented by: Dr. Robert Griebel, Neurosurgeon, Saskatoon

Age: 62
Sex: Male

History:

  • 1992 -- Weakness and numbness in left leg.
  • MRI -- ? AVM mid dorsal spine. Angio normal. Conservative.
    MRI of T-spine showing AVM of mid T-spine

  • 1993 -- Deterioration. Angio repeated. AVM seen. Excised.
  • Intractable pain left leg post-op.
  • Unresponsive to narcotics.
  • 1995 -- Morphine pump implanted at T11-12 at a dose of 5mg daily. Good control.
  • 1998 -- Morphine gradually up to 17mg daily for good pain control.
  • X-Ray now shows catheter at L2-3.
    X-Ray of Lumbar spine showing catheter at L2-3 level when 17mg of morphine was required daily.

  • Catheter re-positioned to T7-8. Morphine requirement dropped to 6mg daily.
    X-Ray of T-spine showing catheter at T7-8. Morphine requirement dropped.

QUESTION:
  1. Is this spontaneous remission cause a drop in the dose requirement of Morphine to control his pain?

  2. Is it related to the repositioning of the tip of the intrathecal catheter in relation to the surgical pathology?

  3. Does it really make a difference in the degree of pain control in intrathecal Morphine infusion where the catheter is, since the drug diffuses throughout the CSF?


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